J R Walton Selected Research

Aluminum

1/2014	Chronic aluminum intake causes Alzheimer's disease: applying Sir Austin Bradford Hill's causality criteria.
9/2013	Selective accumulation of aluminum in cerebral arteries in Alzheimer's disease (AD).
1/2013	Aluminum involvement in the progression of Alzheimer's disease.
1/2012	Aluminum disruption of calcium homeostasis and signal transduction resembles change that occurs in aging and Alzheimer's disease.
1/2012	Cognitive deterioration and associated pathology induced by chronic low-level aluminum ingestion in a translational rat model provides an explanation of Alzheimer's disease, tests for susceptibility and avenues for treatment.
1/2010	Evidence for participation of aluminum in neurofibrillary tangle formation and growth in Alzheimer's disease.
11/2009	Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease.
11/2009	APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease.
9/2007	A sensitive stain for aluminum in undecalcified cancellous bone.
9/2007	An aluminum-based rat model for Alzheimer's disease exhibits oxidative damage, inhibition of PP2A activity, hyperphosphorylated tau, and granulovacuolar degeneration.

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J R Walton Research Topics

Disease

11	Alzheimer Disease (Alzheimer's Disease) 01/2014 - 05/2006
2	Amyloid Plaque 11/2009 - 09/2007
1	Atrophy 01/2014
1	Disease Progression 01/2013
1	Down Syndrome (Down's Syndrome) 01/2013
1	Pain (Aches) 09/2012
1	Dementia (Dementias) 11/2009
1	Wounds and Injuries (Trauma) 11/2009
1	Shock 07/2008
1	Bone Diseases (Bone Disease) 09/2007
1	Inflammation (Inflammations) 12/2005
1	Atherosclerosis 12/2005
1	Neuroblastoma 10/2004

Drug/Important Bio-Agent (IBA)

13	AluminumIBA 01/2014 - 10/2004
3	IronIBA 01/2014 - 10/2004
2	CalciumIBA 01/2012 - 10/2004
2	IonsIBA 11/2009 - 10/2004
1	Aluminum CompoundsIBA 01/2014
1	Biological ProductsIBA 01/2014
1	CytokinesIBA 11/2009
1	NF-kappa B (NF-kB)IBA 11/2009
1	Amyloid (Amyloid Fibrils)IBA 11/2009
1	Proteins (Proteins, Gene)FDA Link 11/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2009
1	CorticosteroneIBA 07/2008
1	Messenger RNA (mRNA)IBA 07/2008
1	Adrenocorticotropic Hormone (ACTH)FDA Link 07/2008
1	Dexamethasone (Maxidex)FDA LinkGeneric 07/2008
1	RNA (Ribonucleic Acid)IBA 07/2008
1	Heterogeneous Nuclear RNAIBA 07/2008
1	PlasticsIBA 09/2007
1	Amyloid beta-PeptidesIBA 01/2007
1	oxidized low density lipoproteinIBA 12/2005
1	LipidsIBA 12/2005
1	MetalsIBA 10/2004
1	CopperIBA 10/2004
1	Culture MediaIBA 10/2004
1	ZincIBA 10/2004

Therapy/Procedure

1	Operative Time 09/2012